Steered molecular dynamics simulations of force-induced protein domain unfolding
نویسندگان
چکیده
منابع مشابه
Steered molecular dynamics simulations of force-induced protein domain unfolding.
Steered molecular dynamics (SMD), a computer simulation method for studying force-induced reactions in biopolymers, has been applied to investigate the response of protein domains to stretching apart of their terminal ends. The simulations mimic atomic force microscopy and optical tweezer experiments, but proceed on much shorter time scales. The simulations on different domains for 0.6 nanoseco...
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ژورنال
عنوان ژورنال: Proteins: Structure, Function, and Genetics
سال: 1999
ISSN: 0887-3585,1097-0134
DOI: 10.1002/(sici)1097-0134(19990601)35:4<453::aid-prot9>3.0.co;2-m